Myeloid-Derived Suppressor Cells Are a Major Source of Wnt5A in the Melanoma Microenvironment and Depend on Wnt5A for Full Suppressive Activity
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DOI: 10.1158/0008-5472.can-20-1238
Abstract: These findings demonstrate that myeloid cells provide a major source of Wnt5A to facilitate metastatic potential in melanoma cells and rely on Wnt5A for their immunosuppressive function. Metastatic dissemination remains a significant barrier to successful… read more here.
Keywords: myeloid; source wnt5a; major source; melanoma ... See more keywords