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Published in 2020 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2020-0164
Abstract: Stimulation of endothelin-B receptors by its agonist, IRL-1620 (INN: sovateltide), provides neuroprotection and neurological and motor function improvement following cerebral ischemia. We investigated the effect of sovateltide on stem and progenitor cells mediated neural regeneration…
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Keywords:
ischemic stroke;
motor function;
cerebral tissue;
sovateltide ... See more keywords
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Published in 2020 at "Stroke"
DOI: 10.1161/str.51.suppl_1.wp161
Abstract: Mitochondrial dysfunction is associated with cerebral ischemic stroke. Sovateltide (IRL-1620; PMZ-1620) undergoing clinical trials (NCT04047563; NCT04046484) has been demonstrated, in preclinical studies, to provide recovery of brain functions when administered following acute cerebral ischemic stroke.…
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Keywords:
vehicle;
compared vehicle;
cerebral ischemic;
sovateltide ... See more keywords