SOX18 enhances the proliferation and migration of airway smooth muscle cells induced by tumor necrosis factor-α via the regulation of Notch1 signaling.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107746
Abstract: Childhood asthma is a frequent chronic disease of pediatric populations. The excessive proliferation and migration of airway smooth muscle cells contribute to airway remodeling during asthma pathogenesis. Sex-determining region on the Y chromosome-related high mobility… read more here.
Keywords: proliferation migration; sox18; muscle cells; smooth muscle ... See more keywords
SOX18 exerts tumor-suppressive functions in papillary thyroid carcinoma through inhibition of Wnt/β-catenin signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.112249
Abstract: Sex-determining region on the Y chromosome-related high mobility group box 18 (SOX18) has emerged as a key tumor-related protein in a wide range of human tumors. Yet, the involvement of SOX18 in papillary thyroid carcinoma… read more here.
Keywords: carcinoma; sox18; papillary thyroid; catenin ... See more keywords
Augmented angiogenic transcription factor, SOX18, is associated with asthma exacerbation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Asthma"
DOI: 10.1080/02770903.2020.1771727
Abstract: Abstract Background Asthma characterized by airway hyperresponsiveness, inflammation, fibrosis, and angiogenesis. SRY-related HMG-box 18 (SOX18) is an important transcription factor involved in angiogenesis, tissue injury, wound-healing, and in embryonic cardiovascular and lymphatic vessels development. The… read more here.
Keywords: transcription; coup tfii; sox18; transcription factor ... See more keywords
Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach
Sign Up to like & getrecommendations! Published in 2018 at "mAbs"
DOI: 10.1080/19420862.2018.1451288
Abstract: ABSTRACT Antibodies are routinely used to study the activity of transcription factors, using various in vitro and in vivo approaches such as electrophoretic mobility shift assay, enzyme-linked immunosorbent assay, genome-wide method analysis coupled with next… read more here.
Keywords: transcription; sox18; transcription factor; transcription factors ... See more keywords
EGR1 Enhances Lymphangiogenesis via SOX18-Mediated Activation of JAK2/STAT3 Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/6448724
Abstract: Background Lymphangiogenesis is a process involved in the pathogenesis of many diseases. Identifying key molecules and pathway targeting this process is critical for lymphatic regeneration-associated disorders. EGR1 is a transcription factor, but its function in… read more here.
Keywords: lymphangiogenesis; tube formation; hdlec cells; sox18 ... See more keywords
Transcription Factor SOX18 Promotes Clear Cell Renal Cell Carcinoma Progression and Alleviates Cabozantinib-Mediated Inhibitory Effects
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.mct-19-0043
Abstract: The transcription factor SOX18, which was initially discovered as an activator of genetic transcription during embryogenesis, is now implicated in many diseases, including cancer, and is associated with the malignant tumor phenotype, angiogenesis, and lymphangiogenesis.… read more here.
Keywords: sox18; clear cell; cell; transcription factor ... See more keywords
Effect of Sox18 on the Induction Ability of Dermal Papilla Cells in Hu Sheep
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology12010065
Abstract: Simple Summary The Sox18 gene is important for the growth and function of dermal papilla cells, but its effect on the induction ability of dermal papilla cells in Hu sheep is not clear. Through experiments,… read more here.
Keywords: sox18; ability; induction ability; papilla cells ... See more keywords
12(S)-HETE induces lymph endothelial cell retraction in vitro by upregulation of SOX18.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of oncology"
DOI: 10.3892/ijo.2018.4378
Abstract: Metastasising breast cancer cells communicate with adjacent lymph endothelia, intravasate and disseminate through lymphatic routes, colonise lymph nodes and finally metastasize to distant organs. Thus, understanding and blocking intravasation may attenuate the metastatic cascade at… read more here.
Keywords: mda mb231; sox18; retraction; intravasation ... See more keywords