Solution structure of the Sox2 DNA-binding domain reveals conformational selection in DNA binding
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DOI: 10.1093/nar/gkaf1121
Abstract: Abstract The transcription factor Sox2 is a master regulator of cell pluripotency. While structural studies have provided insights into its DNA-bound conformation, the mechanisms governing its free-state conformational dynamics and DNA recognition remain elusive. Based… read more here.
Keywords: dna binding; solution structure; sox2 dna; dna ... See more keywords