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   Articles with "sox2 expression" as a keyword



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Sox2 Expression Marks Castration‐Resistant Progenitor Cells in the Adult Murine Prostate

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recommendations! Published in 2019 at "STEM CELLS"

DOI: 10.1002/stem.2987

Abstract: Identification of defined epithelial cell populations with progenitor properties is critical for understanding prostatic development and disease. Here, we demonstrate that Sox2 expression is enriched in the epithelial cells of the proximal prostate adjacent to… read more here.

Keywords: prostate; sox2 expression; castration; sox2 ... See more keywords
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Abstract 3059: SOX2 is a novel biomarker for poor long-term outcomes in oral cancer

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recommendations! Published in 2018 at "Cancer Research"

DOI: 10.1158/1538-7445.am2018-3059

Abstract: Purpose: Sex determining region Y-BOX2 (SOX2), a key regulator of the self-renewal ability of stem cells, plays a role in the initiation and development of head and neck squamous cell carcinoma (HNSCC). However, the association… read more here.

Keywords: cancer; long term; sox2 expression; sox2 ... See more keywords
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Effect of 3q oncogenes SEC62 and SOX2 on lymphatic metastasis and clinical outcome of head and neck squamous cell carcinomas

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recommendations! Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.13986

Abstract: Chromosome 3q26 amplification represents a frequent alteration in head and neck squamous cell carcinomas (HNSCCs). Overexpression of 3q26 encoded genes SEC62 and SOX2 was detected in various cancers, including HNSCCs, indicating their potential function as… read more here.

Keywords: sox2 expression; lymphatic metastasis; sec62 sox2; cell ... See more keywords
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MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.

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recommendations! Published in 2019 at "Oncology reports"

DOI: 10.3892/or.2019.6988

Abstract: Maternal embryonic leucine zipper kinase (MELK) has been reported to serve critical roles in the maintenance of stemness of cancer cells, although its mechanism remains unclear. Since SRY‑box 2 (SOX2) was demonstrated to be involved… read more here.

Keywords: cancer; sox2 expression; melk inhibition; sox2 ... See more keywords