OCT4 and SOX2 Work as Transcriptional Activators in Reprogramming Human Fibroblasts.
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DOI: 10.1016/j.celrep.2017.07.071
Abstract: SOX2 and OCT4, in conjunction with KLF4 and cMYC, are sufficient to reprogram human fibroblasts to induced pluripotent stem cells (iPSCs), but it is unclear if they function as transcriptional activators or as repressors. We… read more here.
Keywords: sox2 work; human fibroblasts; sox2 vp16; oct4 sox2 ... See more keywords