Silencing of Long Noncoding RNA SOX21-AS1 Relieves Neuronal Oxidative Stress Injury in Mice with Alzheimer’s Disease by Upregulating FZD3/5 via the Wnt Signaling Pathway
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-1299-y
Abstract: Alzheimer’s disease (AD) represents a progressive neurodegenerative disorder characterized by distinctive neuropathological changes. Recently, long noncoding RNAs (lncRNAs) have become a key area of interest due to their potential in AD therapy. Hence, the aim… read more here.
Keywords: wnt signaling; sox21 as1; as1; signaling pathway ... See more keywords
CRISPR/cas9-mediated overexpression of long non-coding RNA SRY-box transcription factor 21 antisense divergent transcript 1 regulates the proliferation of osteosarcoma by increasing the expression of mechanistic target of rapamycin kinase and Kruppel like factor 4.
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1995106
Abstract: Osteosarcoma is derived from primitive mesenchymal cells and is the most common primary solid malignant tumor of bone. The cause of osteosarcoma is unclear. In recent years, the role of non-coding sequences in regulating protein… read more here.
Keywords: sox21 as1; proliferation; non coding; lncrna sox21 ... See more keywords
Downregulation of SOX21-AS1 alleviated cisplatin resistance in cervical cancer through Epithelial-messenchymal transition (EMT) inhibition.
Sign Up to like & getrecommendations! Published in 2022 at "Rejuvenation research"
DOI: 10.1089/rej.2022.0009
Abstract: Cisplatin is widely used in chemotherapies in cervical cancer (CC). Nevertheless, drug resistance in cancer patients poses a major threat to efficacy of treatment. To explore the underlying modulatory mechanism of SOX21-AS1 in cisplatin resistance… read more here.
Keywords: cervical cancer; sox21 as1; cancer; cisplatin resistance ... See more keywords