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   Articles with "sox5" as a keyword



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NEAT1/miR‐193a‐3p/SOX5 axis regulates cartilage matrix degradation in human osteoarthritis

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recommendations! Published in 2019 at "Cell Biology International"

DOI: 10.1002/cbin.11291

Abstract: Long non‐coding RNAs (lncRNAs) were reported to be involved in the progression of osteoarthritis (OA). The aim of this work was to explore the functional role of lncRNA nuclear‐enriched abundant transcript 1 (NEAT1) in OA.… read more here.

Keywords: sox5 axis; neat1 mir; 193a sox5; sox5 ... See more keywords

Transcriptional regulation of CRMP5 controls neurite outgrowth through Sox5

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recommendations! Published in 2017 at "Cellular and Molecular Life Sciences"

DOI: 10.1007/s00018-017-2634-6

Abstract: Transcriptional regulation of proteins involved in neuronal polarity is a key process that underlies the ability of neurons to transfer information in the central nervous system. The Collapsin Response Mediator Protein (CRMP) family is best… read more here.

Keywords: crmp5; neurite outgrowth; sox5; transcriptional regulation ... See more keywords
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Silencing of the Drosophila ortholog of SOX5 leads to abnormal neuronal development and behavioral impairment

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recommendations! Published in 2017 at "Human Molecular Genetics"

DOI: 10.1093/hmg/ddx051

Abstract: SOX5 encodes a transcription factor that is expressed in multiple tissues including heart, lung and brain. Mutations in SOX5 have been previously found in patients with amyotrophic lateral sclerosis (ALS) and developmental delay, intellectual disability… read more here.

Keywords: sox5 leads; drosophila ortholog; sox5; ortholog sox5 ... See more keywords

HuR stabilizes lnc-Sox5 mRNA to promote tongue carcinogenesis

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recommendations! Published in 2017 at "Biochemistry (Moscow)"

DOI: 10.1134/s0006297917040046

Abstract: Long noncoding RNAs (lncRNAs) have been recently regarded as systemic regulators in multiple biological processes including tumorigenesis. In this study, we report an ultra-highly expressed lncRNA, lnc-Sox5, in tongue tumor tissues. The results imply that… read more here.

Keywords: lnc sox5; tca8113; sox5; hur ... See more keywords
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SOX5 promotes cell invasion and metastasis via activation of Twist-mediated epithelial–mesenchymal transition in gastric cancer

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recommendations! Published in 2019 at "OncoTargets and therapy"

DOI: 10.2147/ott.s197087

Abstract: Background Sex-determining region Y-box protein 5 (SOX5) has been demonstrated to be implicated in oncogenic function in various types of cancers. However, the role of SOX5 in gastric cancer (GC) remains poorly elucidated. Herein, we… read more here.

Keywords: metastasis; gastric cancer; epithelial mesenchymal; twist mediated ... See more keywords
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SOX5 promotes cell growth and migration through modulating DNMT1/p21 pathway in bladder cancer

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recommendations! Published in 2022 at "Acta Biochimica et Biophysica Sinica"

DOI: 10.3724/abbs.2022075

Abstract: Bladder cancer (BC) is one of the most prevalent and life-threatening cancers among the male population worldwide. Sex determining region Y-box protein 5 (SOX5) plays important roles in a variety of human cancers. However, little… read more here.

Keywords: p21; sox5; growth; cell growth ... See more keywords