SOX8 is essential for male sexual differentiation in the Chinese soft-shelled turtle Pelodiscus sinensis.
Sign Up to like & getrecommendations! Published in 2023 at "Biology of reproduction"
DOI: 10.1093/biolre/ioad033
Abstract: SOX8, which belongs to SOXE transcription factor subfamily together with SOX9, participates in sex differentiation and testicular development by enhancing the function of SOX9 in mammals. However, the functional role of SOX8 in sex differentiation… read more here.
Keywords: sox8; shelled turtle; chinese soft; differentiation ... See more keywords
SOX8 acts as a prognostic factor and mediator to regulate the progression of triple-negative breast cancer.
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DOI: 10.1093/carcin/bgz034
Abstract: The molecular mechanisms underlying triple-negative breast cancer (TNBC) pathology are not fully understood. Here, we reviewed the SOX8 transcript level in 24 types of cancer and normal tissues and the SOX8 expression pattern in breast… read more here.
Keywords: sox8; breast cancer; tnbc; cancer ... See more keywords
SOX8 Affects Tumoral SPARC Expression by Regulating EZH2 to Attenuate Effectiveness of albumin-bound paclitaxel in PDAC
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DOI: 10.7150/ijbs.64752
Abstract: Pancreatic cancer is a dismal malignancy with poor prognosis. In spite of progress in surgical technology, chemotherapy is still the cornerstone in the multi-disciplinary treatment. Albumin-bound paclitaxel is a first-line treatment for PDAC patients. Yet… read more here.
Keywords: albumin bound; sox8; expression; bound paclitaxel ... See more keywords