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   Articles with "sox9" as a keyword



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Platelet lysate induces chondrogenic differentiation of umbilical cord‐derived mesenchymal stem cells by regulating the lncRNA H19/miR‐29b‐3p/SOX9 axis

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recommendations! Published in 2020 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13002

Abstract: Platelet lysate (PL) has been shown to induce chondrogenic differentiation of human umbilical cord‐derived mesenchymal stem cells (hUCMSCs). However, the underlying mechanism is still not clear. The aim of this study was to investigate whether… read more here.

Keywords: h19 mir; chondrogenic differentiation; sox9; mir 29b ... See more keywords
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Differential activity of transcription factor Sox9 in early and adult oligodendroglial progenitor cells.

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recommendations! Published in 2023 at "Glia"

DOI: 10.1002/glia.24373

Abstract: The high-mobility-group domain-containing transcription factor Sox9 confers glial competence to neuroepithelial precursors in the developing central nervous system and is an important determinant of astroglial and oligodendroglial specification. In oligodendroglial cells, it remains expressed in… read more here.

Keywords: sox9; adult; factor sox9; transcription factor ... See more keywords
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TGFβ signaling controls intrahepatic bile duct development may through regulating the Jagged1‐Notch‐Sox9 signaling axis

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recommendations! Published in 2018 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.26304

Abstract: Due to the inherent limitations of the mouse models, the molecular mechanism of TGFβ signaling involved in the development of intrahepatic bile ducts (IHBDs) has been investigated little. Here, we investigated the role of TGFβ… read more here.

Keywords: tgf signaling; notch; tgf; sox9 ... See more keywords

Increase of SOX9 promotes hepatic ischemia/reperfusion (IR) injury by activating TGF-β1.

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recommendations! Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.06.005

Abstract: Ischemia/reperfusion (IR) injury causes damage in aerobically metabolizing organs or tissues, which is an essential injury mechanism in various clinical settings. SRY-related high mobility group-Box gene 9 (SOX9) is a transcription factor of the SRY… read more here.

Keywords: apoptosis; sox9; ischemia reperfusion; reperfusion injury ... See more keywords
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SOX9 dependent FOXA1 expression promotes tumorigenesis in lung carcinoma.

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recommendations! Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.05.169

Abstract: The malignant proliferation is one of the major characteristic for tumor cells, however the mechanism of lung cancer cells uncontrollable proliferation is still confusing. This study investigated the mechanism of up-regulated FOXA1 in lung cancer… read more here.

Keywords: foxa1; expression; sox9; lung cancer ... See more keywords
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Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis.

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recommendations! Published in 2018 at "Cancer cell"

DOI: 10.1016/j.ccell.2018.01.020

Abstract: Trait-associated loci often map to genomic regions encoding long noncoding RNAs (lncRNAs), but the role of these lncRNAs in disease etiology is largely unexplored. We show that a pair of sense/antisense lncRNA (6p22lncRNAs) encoded by… read more here.

Keywords: pair; sense antisense; antisense lncrna; sox9 ... See more keywords
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Circ_0075825 promotes gastric cancer progression via adsorbing miR-432-5p to modulate SOX9

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recommendations! Published in 2022 at "Clinics"

DOI: 10.1016/j.clinsp.2022.100018

Abstract: Highlights • Circ_0075825 is highly expressed in gastric cancer tissues.• Circ_0075825 promotes the malignant biological behaviors of gastric cancer cells.• Circ_0075825 functions as a molecular sponge to repress miR-432-5p and up-regulate SOX9. read more here.

Keywords: mir 432; 0075825 promotes; circ 0075825; gastric cancer ... See more keywords
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Yap-Sox9 signaling determines hepatocyte plasticity and lineage-specific hepatocarcinogenesis.

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recommendations! Published in 2021 at "Journal of hepatology"

DOI: 10.1016/j.jhep.2021.11.010

Abstract: BACKGROUND & AIMS Primary liver tumors contain distinct subtypes. A subset of iCCAs can arise from cell fate reprogramming of mature hepatocytes in mouse models. However, the underpinning of cell fate plasticity during hepatocarcinogenesis is… read more here.

Keywords: hepatocarcinogenesis; plasticity; sox9; yap activation ... See more keywords
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Identification of Human Temporomandibular Joint Fibrocartilage Stem Cells with Distinct Chondrogenic Capacity.

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recommendations! Published in 2020 at "Osteoarthritis and cartilage"

DOI: 10.1016/j.joca.2020.02.835

Abstract: OBJECTIVE This study was aimed to identify the residence of human fibrocartilage stem cells (hFCSCs), characterize their stem cell properties and investigate the functional mechanisms which regulate FCSCs toward chondrogenic differentiation during cartilage homeostasis and… read more here.

Keywords: fibrocartilage stem; hfcscs; sox9; stem ... See more keywords
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microRNA-30e up-regulation alleviates myocardial ischemia-reperfusion injury and promotes ventricular remodeling via SOX9 repression.

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recommendations! Published in 2020 at "Molecular immunology"

DOI: 10.1016/j.molimm.2020.11.009

Abstract: AIM At present, studies have focused on microRNAs (miRNAs) in myocardial ischemia-reperfusion injury (MI/RI). But the specific role of miR-30e hasn't been fully explored. Thus, this study is to uncover the mechanism of miR-30e in… read more here.

Keywords: 30e regulation; mir 30e; sox9; ventricular remodeling ... See more keywords
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MiR-126 Regulates Properties of SOX9+ Liver Progenitor Cells during Liver Repair by Targeting Hoxb6

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recommendations! Published in 2020 at "Stem Cell Reports"

DOI: 10.1016/j.stemcr.2020.07.005

Abstract: Summary Liver progenitor cells (LPCs) have a remarkable contribution to the hepatocytes and ductal cells when normal hepatocyte proliferation is severely impaired. As a biomarker for LPCs, Sry-box 9 (Sox9) plays critical roles in liver… read more here.

Keywords: progenitor cells; mir 126; liver progenitor; sox9 ... See more keywords