Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions
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DOI: 10.1371/journal.pgen.1007346
Abstract: The growth plate mediates bone growth where SOX9 and GLI factors control chondrocyte proliferation, differentiation and entry into hypertrophy. FOXA factors regulate hypertrophic chondrocyte maturation. How these factors integrate into a Gene Regulatory Network (GRN)… read more here.
Keywords: foxa; sox9; differentiation transitions; sox9 gli ... See more keywords