Spatiotemporal dynamic changes, proliferation, and differentiation characteristics of Sox9-positive cells after severe complete transection spinal cord injury
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DOI: 10.1016/j.expneurol.2020.113556
Abstract: Studying the spatiotemporal dynamic changes of various cells following spinal cord injury (SCI) is of great significance for understanding the pathological processes of SCI. Changes in the characteristics of Sox9-positive cells, which are widely present… read more here.
Keywords: sox9 positive; positive cells; dynamic changes; spatiotemporal dynamic ... See more keywords
MBRS-10. QUIESCENT SOX9-POSITIVE CELLS BEHIND MYC DRIVEN MEDULLOBLASTOMA RECURRENCE
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DOI: 10.1093/neuonc/noaa222.528
Abstract: Abstract Tumor recurrence is the leading cause of death in medulloblastoma, the most frequent malignant pediatric brain tumor. Recurrence occurs when subpopulations of cancer cells evade standard therapy by acquiring features of immune escape, metastatic… read more here.
Keywords: recurrence; medulloblastoma; sox9 positive; positive cells ... See more keywords
CNSC-22. TARGETING SOX9-POSITIVE THERAPY-RESISTANT MEDULLOBLASTOMA WITH A NOVEL SUICIDE GENE THERAPY
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DOI: 10.1093/neuonc/noaf201.0230
Abstract: The transcription factor SOX9 is a marker of poor prognosis and therapy resistance in medulloblastoma, one of the most common malignant brain tumor types in children. Knockdown or downregulation of SOX9 inhibits medulloblastoma recurrence in… read more here.
Keywords: therapy; sox9 positive; gene therapy; suicide gene ... See more keywords