Iodine-Mediated Electrochemical C(sp2)-H Amination: Switchable Synthesis of Indolines and Indoles.
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DOI: 10.1021/acs.orglett.0c01821
Abstract: A metal-free electrochemical intramolecular C(sp2)-H amination using iodine as a mediator was developed. This method enables a switchable synthesis of indoline and indole derivatives, respectively, from easily available 2-vinyl anilines. read more here.
Keywords: switchable synthesis; iodine mediated; sp2 amination;
Trisulfur-Radical-Anion-Triggered C(sp2)-H Amination of Electron-Deficient Alkenes.
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DOI: 10.1021/acs.orglett.0c03846
Abstract: A trisulfur-radical-anion (S3̇-)-triggered C(sp2)-H amination of α,β-unsaturated carbonyl derivatives with simple amines has been demonstrated. This protocol provides convenient access to a variety of synthetically valuable N-unprotected and secondary β-enaminones with absolute Z selectivity and… read more here.
Keywords: trisulfur radical; triggered sp2; sp2 amination; radical anion ... See more keywords
Ir-Catalyzed Intramolecular Transannulation/C(sp2)-H Amination of 1,2,3,4-Tetrazoles by Electrocyclization.
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DOI: 10.1021/jacs.8b05343
Abstract: An efficient strategy for the intramolecular denitrogenative transannulation/C(sp2)-H amination of 1,2,3,4-tetrazoles bearing C8-substituted arenes, heteroarenes, and alkenes is described. The process involves the generation of the metal-nitrene intermediate from tetrazole by the combination of [Cp*IrCl2]2… read more here.
Keywords: transannulation sp2; amination tetrazoles; sp2 amination;
Cp*Ir(iii)- and Cp*Rh(iii)-catalyzed C(sp2)–H amination of arenes using thioethers as directing groups
Sign Up to like & getrecommendations! Published in 2021 at "Organic chemistry frontiers"
DOI: 10.1039/d0qo01353f
Abstract: A mild and selective Cp*Ir(iii)- and Cp*Rh(iii)-catalyzed direct C(sp2)–H amination of arenes and three types of nitrene precursor reagents is reported, with the assistance of a thioether directing group. read more here.
Keywords: iii iii; sp2 amination; catalyzed sp2; iii catalyzed ... See more keywords