Zn(II)-Catalyzed Addition of Aromatic/Heteroaromatic C(sp2)-H to Azoalkenes: A Polarity-Reversed Arylation of Carbonyl Compounds.
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DOI: 10.1021/acs.orglett.9b01628
Abstract: An umpolung α-(hetero)arylation strategy that involves the Michael-type reaction between electron-rich (hetero)aromatic substrates and azoalkenes is developed. The reaction proceeds under very mild conditions at room temperature and in the presence of inexpensive, nontoxic ZnCl2… read more here.
Keywords: catalyzed addition; addition aromatic; sp2 azoalkenes; arylation ... See more keywords