Construction of C(sp2)-Si Bonds via Ligand-Promoted C-C Bonds Cleavage of Unstrained Ketones.
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DOI: 10.1021/acs.orglett.2c02841
Abstract: Herein, we report an efficient palladium-catalyzed silylation of aryl and alkenyl ketones via C-C bond cleavage and C-Si bond formation. This protocol features high efficiency and broad substrate scope. Further applications in the late-stage diversification… read more here.
Keywords: via ligand; cleavage; ligand promoted; bonds via ... See more keywords
Dealkenylative Thiylation of C(sp3)-C(sp2) Bonds.
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DOI: 10.1021/acs.orglett.9b03186
Abstract: Carbon-carbon bond fragmentations are useful methods for the functionalization of molecules. The value of such cleavage events is maximized when paired with subsequent bond formation. Herein we report a protocol for the cleavage of an… read more here.
Keywords: sp3; bond; dealkenylative thiylation; thiylation sp3 ... See more keywords
Photocatalytic Methylation of Nonactivated sp3 and sp2 C–H Bonds Using Methanol on GaN
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DOI: 10.1021/acscatal.0c00881
Abstract: Although the development of C-H functionalization methods has enlightened many new reactivities in chemistry, the direct functionalization of unactivated C-H bonds, which are particularly common in... read more here.
Keywords: methylation nonactivated; nonactivated sp3; bonds using; photocatalytic methylation ... See more keywords
N-Iminopyridinium ylide-directed, cobalt-catalysed coupling of sp2 C-H bonds with alkynes.
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DOI: 10.1039/d0cc05294a
Abstract: N-Iminopyridinium ylides are competent monodentate directing groups for cobalt-catalysed annulation of sp2 C-H bonds with internal alkynes. The pyridine moiety in the ylide serves as an internal oxidant and is cleaved during the reaction. The… read more here.
Keywords: sp2 bonds; iminopyridinium ylide; ylide directed; cobalt catalysed ... See more keywords
Multiple annulations of inert C(sp2)-H bonds with alkynes.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00172a
Abstract: Transition-metal catalyzed directing group (DG) assisted annulation of inert C-H bonds leads to the formation of complex molecular frameworks from readily accessible substrates. Thus, multiple annulation of less functionalized substrates with unsaturated species leads to… read more here.
Keywords: bonds alkynes; type involves; annulation; arene bond ... See more keywords