Native Amino Group Directed Site-Selective ε-C(sp2)-H Iodination of Primary Amines.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.2c04288
Abstract: Selective remote C-H activating amines using unmodified NH2 as a native directing group demonstrate compelling synthetic utilities. The 3-arylpropan-1-amine moiety is present in many drugs and candidates in clinical trials. Selective iodination of 3-arylpropan-1-amines on… read more here.
Keywords: native amino; sp2 iodination; selective sp2; group ... See more keywords
C(sp2)–H Iodination by a Rhodium(III) Complex Supported by a Redox-active Ligand Bearing Amidophenolato Moieties
Sign Up to like & getrecommendations! Published in 2020 at "Chemistry Letters"
DOI: 10.1246/cl.200178
Abstract: C(sp2)–H iodination of m-xylene promoted by a rhodium(III) complex supported by a redox-active ligand, (nBu4N)[RhIIIL3−(MeCN)Cl] (1Cl), is reported. The iodination reaction involves an electrophili... read more here.
Keywords: iodination; supported redox; complex supported; sp2 iodination ... See more keywords