Elemental‐Sulfur‐Promoted C(sp3)−H Activation of Methyl Heteroarenes Leading to Thioamides
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DOI: 10.1002/ajoc.201700532
Abstract: A novel approach to access bioactive thioamides is developed based on elemental sulfur promoted C(sp3)-H activation of methyl heteroarenes. This transformation could successfully furnish a series of heterocyclic thioamides with excellent yields and it could… read more here.
Keywords: methyl heteroarenes; sp3 activation; sulfur promoted; promoted sp3 ... See more keywords
Palladium/Benzoic Acid-Catalyzed Regio- and Stereoselective Polymerization of Internal Diynes and Diols through C(sp3)–H Activation
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DOI: 10.1021/acsmacrolett.9b00448
Abstract: The C–H activation has been a hot research area in organic chemistry, and the most difficult one is the C(sp3)–H activation. Although the C–H activation has been introduced to the research of synthetic polymer chemistry,… read more here.
Keywords: activation; sp3 activation; benzoic acid; polymerization ... See more keywords
sp3 C–H activation via exo-type directing groups
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Science"
DOI: 10.1039/c7sc04768a
Abstract: The application of exo-type directing groups (DGs) has led to the discovery of a wide range of novel C(sp3)–H activation methods, which allow efficient and site-selective functionalization of alcohol and amide derivatives. read more here.
Keywords: exo type; type directing; directing groups; sp3 activation ... See more keywords
Transition metal-catalyzed sp3 C-H activation and intramolecular C-N coupling to construct nitrogen heterocyclic scaffolds.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc06609h
Abstract: Nitrogen heterocycles are of great medicinal importance, and the construction of nitrogen heterocyclic scaffolds has been one of the focuses in synthetic organic chemistry. Recently, the strategy of transition metal-catalyzed sp3 C-H activation and intramolecular… read more here.
Keywords: nitrogen; transition metal; heterocyclic scaffolds; nitrogen heterocyclic ... See more keywords
Selective propargylic C(sp3)–H activation of methyl-substituted alkynes versus [2 + 2] cycloaddition at a titanium imido template
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DOI: 10.1039/d1sc04334j
Abstract: The reaction of the titanium imido complex 1b with 2-butyne leads to the formation of the titanium azadiene complex 2a at ambient temperature instead of yielding the archetypical [2 + 2] cycloaddition product (titanaazacyclobutene) which… read more here.
Keywords: titanium imido; cycloaddition; propargylic sp3; titanium ... See more keywords
Direct C(sp3)–H Activation of Carboxylic Acids
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DOI: 10.1055/s-0039-1690720
Abstract: Carboxylic acids are important in a variety of research fields and applications. As a result, substantial efforts have been directed towards the C–H functionalization of such compounds. While the use of the carboxylic acid moiety… read more here.
Keywords: activation carboxylic; carboxylic acids; aliphatic carboxylic; sp3 activation ... See more keywords