Oxidative C(sp3)–H amidation of tertiary arylamines with nitriles
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DOI: 10.1039/c8qo00794b
Abstract: The first amidation of tertiary arylamines with nitriles via a cascade dehydrogenation/heterocoupling/addition reaction between α-C–H bonds of tertiary amines and nitrogen atoms of nitriles has been developed. The use of copper(I) iodide as a Lewis… read more here.
Keywords: oxidative sp3; amidation tertiary; tertiary arylamines; sp3 amidation ... See more keywords
Dirhodium-Catalyzed Chemo- and Site-Selective C–H Amidation of N,N-Dialkylanilines
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DOI: 10.1055/a-1334-6450
Abstract: A method for dirhodium-catalyzed C(sp3)-H amidation of N,N-dimethylanilines was developed. Chemoselective C(sp3)-H amidation of N-methyl group proceeded exclusively in the presence of C(sp2)-H bonds of the electron-rich aromatic ring. Site-selective C(sp3)-H amidation proceeded exclusively at… read more here.
Keywords: site selective; sp3 amidation; amidation; dirhodium catalyzed ... See more keywords