Benzylic C(sp3)‐H Azidation: Copper vs Iron Catalysis
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DOI: 10.1002/hlca.202400004
Abstract: The generation of benzylic radicals through hydrogen atom abstraction (HAT) has been a recent research focus and various C(sp3)‐H bond functionalization protocols have been developed relying on this elementary step. We report herein copper‐ and… read more here.
Keywords: azidation copper; azidation; benzylic sp3; sp3 azidation ... See more keywords
Iron Catalysis of C(sp3)-H Azidation Using a Heteroarene Radical Cation Strategy.
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DOI: 10.1021/acs.orglett.3c00330
Abstract: The FeIII(phen)3 catalysis of the benzylic C(sp3)-H azidation of indoles has been investigated. The Fe(III) complex can selectively oxidize indoles to form arene radical cations, which are transformed into benzylic C(sp3) radical intermediates. This strategy… read more here.
Keywords: sp3 azidation; catalysis; strategy; iron catalysis ... See more keywords
Decatungstate-photocatalysed C(sp3)-H azidation.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00425a
Abstract: C-H Azidation is an increasingly important tool for bioconjugation, materials chemistry, and the synthesis of nitrogen-containing natural products. While several approaches have been developed, these often require exotic and energetic reagents, expensive photocatalysts, or both.… read more here.
Keywords: sp3 azidation; azidation; decatungstate photocatalysed; photocatalysed sp3 ... See more keywords