PdII‐Catalyzed γ‐C(sp3)–H (Hetero)arylation of Ketones Using Acetohydrazide as the Transient Directing Group
Sign Up to like & getrecommendations! Published in 2025 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.202500289
Abstract: Pd(II)‐catalyzed γ‐C(sp3)–H (hetero)arylation of aliphatic ketones is developed using acetohydrazide as the transient directing group (TDG). The reaction is facilitated by a crucial 2‐pyridone ligand via the 5,6‐membered fused palladacycle intermediate, enabling the smooth γ‐C(sp3)–H… read more here.
Keywords: catalyzed sp3; sp3 hetero; arylation; hetero arylation ... See more keywords