Exploring sequence space in search of functional enzymes using microfluidic droplets.
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DOI: 10.1016/j.cbpa.2017.02.018
Abstract: Screening of enzyme mutants in monodisperse picoliter compartments, generated at kilohertz speed in microfluidic devices, is coming of age. After a decade of proof-of-principle experiments, workflows have emerged that combine existing microfluidic modules to assay… read more here.
Keywords: sequence space; exploring sequence; search functional; space search ... See more keywords