Targeting Alzheimer's disease by investigating previously unexplored chemical space surrounding the cholinesterase inhibitor donepezil.
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DOI: 10.1016/j.ejmech.2016.10.036
Abstract: A series of twenty seven acetylcholinesterase inhibitors, as potential agents for the treatment of Alzheimer's disease, were designed and synthesised based upon previously unexplored chemical space surrounding the molecular skeleton of the drug donepezil, which… read more here.
Keywords: previously unexplored; alzheimer disease; disease; chemical space ... See more keywords