Shortened Spadin Analogs Display Better TREK-1 Inhibition, In Vivo Stability and Antidepressant Activity
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DOI: 10.3389/fphar.2017.00643
Abstract: Depression is a devastating mental disorder that affects 20% of the population worldwide. Despite their proven efficacy, antidepressants present a delayed onset of action and serious adverse effects. Seven years ago, we described spadin (PE… read more here.
Keywords: antidepressant activity; spadin analogs; trek; stability ... See more keywords