Acting on the CFTR Membrane-Spanning Domains Interface Rescues Some Misfolded Mutants
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DOI: 10.3390/ijms232416225
Abstract: ABC transporters are large membrane proteins sharing a complex architecture, which comprises two nucleotide-binding domains (NBDs) and two membrane-spanning domains (MSDs). These domains are susceptible to mutations affecting their folding and assembly. In the CFTR… read more here.
Keywords: membrane spanning; spanning domains; cftr; cftr membrane ... See more keywords