SPARC expression is associated with hepatic injury in rodents and humans with non-alcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-18981-9
Abstract: Mechanisms that control progression from simple steatosis to steato-hepatitis and fibrosis in patients with non-alcoholic fatty liver disease (NAFLD) are unknown. SPARC, a secreted matricellular protein, is over-expressed in the liver under chronic injury. Contribution… read more here.
Keywords: sparc; non alcoholic; sparc expression; disease ... See more keywords
Prognostic significance of SPARC expression in non-small cell lung cancer: A meta-analysis and bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2022 at "Oncology Letters"
DOI: 10.3892/ol.2022.13532
Abstract: The aim of the present study was to elucidate the significance of secreted protein acidic and cysteine rich (SPARC) expression in non-small cell lung cancer (NSCLC) in terms of clinicopathology, immune-cell infiltration and survival prognosis.… read more here.
Keywords: lung cancer; expression; analysis; sparc expression ... See more keywords
Mesenchymal stem cells induce tumor stroma formation and epithelial-mesenchymal transition through SPARC expression in colorectal cancer
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DOI: 10.3892/or.2021.8055
Abstract: Tumor-stroma interactions serve a crucial role in the development of colorectal cancer (CRC), in which secreted protein acidic and rich in cysteine (SPARC) has been implicated. Due to interactions between cancer and stromal cells [mesenchymal… read more here.
Keywords: sparc expression; expression; crc; cancer ... See more keywords