New triorganotin(IV) complexes of quinolone antibacterial drug sparfloxacin: Synthesis, structural characterization, DFT studies and biological activity
Sign Up to like & getrecommendations! Published in 2018 at "Applied Organometallic Chemistry"
DOI: 10.1002/aoc.4324
Abstract: A new series of triorganotin(IV) complexes of sparfloxacin (HL) having general formula R3SnL (where L is the monoanion of sparfloxacin (HL) and R = Me (1)/n-Bu (2)/Ph (3)/Cy (4)) have been synthesized and characterized by… read more here.
Keywords: sparfloxacin; dft; new triorganotin; activity ... See more keywords
PLGA nanoformulation of sparfloxacin enhanced antibacterial activity with photoprotective potential under ambient UV-R exposure.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.02.028
Abstract: Sparfloxacin (SPFX) is a broad spectrum antibiotic which inhibits bacterial DNA gyrase enzyme activity. However, photodegradation in the presence of UVA limits its antibacterial activity and induces phototoxicity. Thus, to encounter this problem, we have… read more here.
Keywords: sparfloxacin; exposure; antibacterial activity; spfx ... See more keywords