A spatial atlas of human gastrointestinal acute GVHD reveals epithelial and immune dynamics underlying disease pathophysiology.
Sign Up to like & getrecommendations! Published in 2025 at "Science translational medicine"
DOI: 10.1126/scitranslmed.adu6032
Abstract: Acute graft-versus-host disease (aGVHD) is a severe complication of allogeneic hematopoietic stem cell transplantation, driven by alloreactive donor T cells in the gut. However, the roles of additional donor and host cells in this process… read more here.
Keywords: disease; immune dynamics; spatial atlas; across individuals ... See more keywords
LncSpA: LncRNA Spatial Atlas of Expression across Normal and Cancer Tissues
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/0008-5472.can-19-2687
Abstract: LncSpA is a new interactive resource that provides the spatial expression pattern of lncRNA across thousands of normal and cancer samples representing major tissue types. Long noncoding RNAs (lncRNA) play important roles in maintaining morphology… read more here.
Keywords: expression; spatial expression; cancer; spatial atlas ... See more keywords
Abstract 4900: Spatial Atlas of Human Anatomy (SAHA): A subcellular, multiscale spatial odyssey of immune and gastrointestinal tissues and tumors
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-4900
Abstract: The Spatial Atlas of Human Anatomy (SAHA) is a foundational effort to map 250 million cells and transcriptomes and proteomes of 30 non-diseased organs from healthy adults at two spatial scales: whole transcriptome of histological… read more here.
Keywords: anatomy saha; cancer; atlas human; spatial atlas ... See more keywords