Thalamic Proteome Changes and Behavioral Impairments in Thiamine-deficient Rats
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.06.003
Abstract: Thiamine deficiency (TD) has been used as an experimental model in rodents to study the molecular mechanisms of neurodegeneration and its association with behavioral changes. The aims of the present study were to investigate the… read more here.
Keywords: changes behavioral; spatial cognitive; thalamic proteome; impairments thiamine ... See more keywords
Neonatal Lipopolysaccharide Challenge Induces Long-lasting Spatial Cognitive Impairment and Dysregulation of Hippocampal Histone Acetylation in Mice
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.12.001
Abstract: Neonatal inflammation induces long-term effects on brain function. We investigated the effects of systematic neonatal inflammation using lipopolysaccharide (LPS) injection at postnatal day 3 (P3) and P5 in a mouse model of spatial memory capacity… read more here.
Keywords: spatial cognitive; histone acetylation; acetylation; cognitive impairment ... See more keywords
Riluzole ameliorates soluble Aβ1–42-induced impairments in spatial memory by modulating the glutamatergic/GABAergic balance in the dentate gyrus
Sign Up to like & getrecommendations! Published in 2021 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2020.110077
Abstract: Soluble amyloid beta (Aβ) is believed to contribute to cognitive deficits in the early stages of Alzheimer's disease (AD). Increased soluble Aβ1-42 in the hippocampus is closely correlated with spatial learning and memory deficits in… read more here.
Keywords: cognitive deficits; spatial cognitive; excitation; soluble induced ... See more keywords
Effects of methamphetamine abuse on spatial cognitive function
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-23828-y
Abstract: Methamphetamine (MA) abuse has been rising rapidly over the past decade, however, its impact in spatial cognitive function remains unknown. To understand its effect on visuospatial ability and spatial orientation ability, 40 MA users and… read more here.
Keywords: task; orientation; spatial cognitive; methamphetamine abuse ... See more keywords
Effects of GABAB receptor activation on spatial cognitive function and hippocampal neurones in rat models of type 2 diabetes mellitus
Sign Up to like & getrecommendations! Published in 2018 at "Bioscience Reports"
DOI: 10.1042/bsr20171184
Abstract: The present study was conducted with the aim being to investigate the effect γ-aminobutyric acid type B (GABAB) receptor activation have on spatial cognitive function and hippocampal neurones found in the rat models of type… read more here.
Keywords: t2dm; hippocampal neurones; spatial cognitive; cognitive function ... See more keywords
How does spatial cognitive style affect indoor fire evacuation wayfinding in mobile virtual reality?
Sign Up to like & getrecommendations! Published in 2023 at "Cartography and Geographic Information Science"
DOI: 10.1080/15230406.2023.2176928
Abstract: ABSTRACT In emergency situations such as fire evacuation, indoor wayfinding is a complex and challenging task that is closely related to spatial cognition and spatial ability. This study discusses the indoor wayfinding ability of evacuees… read more here.
Keywords: spatial cognitive; fire evacuation; style; cognitive style ... See more keywords
Alzheimer‐like tau accumulation in dentate gyrus mossy cells induces spatial cognitive deficits by disrupting multiple memory‐related signaling and inhibiting local neural circuit
Sign Up to like & getrecommendations! Published in 2022 at "Aging Cell"
DOI: 10.1111/acel.13600
Abstract: Abnormal tau accumulation and spatial memory loss constitute characteristic pathology and symptoms of Alzheimer disease (AD). Yet, the intrinsic connections and the mechanism between them are not fully understood. In the current study, we observed… read more here.
Keywords: spatial cognitive; mossy cell; accumulation; mossy ... See more keywords
Effects of environmental enrichment on behavioral and spatial cognitive deficits in morphine-dependent and -withdrawn rats.
Sign Up to like & getrecommendations! Published in 2017 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2016-0168
Abstract: This study was designed to examine the effect of environmental enrichment during morphine dependence and withdrawal on morphine-induced behavioral and spatial cognitive disorders in morphine-withdrawn rats. Adult male Wistar rats (190 ± 20 g) were… read more here.
Keywords: behavioral spatial; morphine; spatial cognitive; withdrawn rats ... See more keywords
Research progress on vestibular dysfunction and visual–spatial cognition in patients with Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2023.1153918
Abstract: Alzheimer’s disease (AD) or vestibular dysfunction may impair visual–spatial cognitive function. Recent studies have shown that vestibular dysfunction is increasingly common in patients with AD, and patients with AD with vestibular impairment show more visual–spatial… read more here.
Keywords: visual spatial; alzheimer disease; spatial cognitive; vestibular dysfunction ... See more keywords