Spatial learning and long‐term memory impairments in RasGrf1 KO, Pttg1 KO, and double KO mice
Sign Up to like & getrecommendations! Published in 2018 at "Brain and Behavior"
DOI: 10.1002/brb3.1089
Abstract: RasGrf1 is a guanine‐nucleotide releasing factor that enhances Ras activity. Human PTTG1 is an oncoprotein found in pituitary tumors and later identified as securin, a protein isolated from yeast with a reported role in chromosome… read more here.
Keywords: memory; spatial learning; long term; rasgrf1 pttg1 ... See more keywords
Testing domain general learning in an Australian lizard
Sign Up to like & getrecommendations! Published in 2018 at "Animal Cognition"
DOI: 10.1007/s10071-018-1194-y
Abstract: A key question in cognition is whether animals that are proficient in a specific cognitive domain (domain specific hypothesis), such as spatial learning, are also proficient in other domains (domain general hypothesis) or whether there… read more here.
Keywords: learning; domain specific; spatial learning; general learning ... See more keywords
Spatial learning in Japanese eels (Anguilla japonica)
Sign Up to like & getrecommendations! Published in 2019 at "Animal Cognition"
DOI: 10.1007/s10071-019-01320-y
Abstract: Japanese eels ( Anguilla japonica ) were trained on a Morris-type spatial learning task. There were four tubes in a pool, but the eels could hide in only one of these. The eels learned the… read more here.
Keywords: spatial learning; open tube; learning japanese; eels anguilla ... See more keywords
Expression of BC1 Impairs Spatial Learning and Memory in Alzheimer’s Disease Via APP Translation
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0820-z
Abstract: Aggregation of amyloid-β (Aβ) peptides, which are the cleavage products of amyloid precursor protein (APP), is a major pathological hallmark in the brain of Alzheimer’s disease (AD). Now, we know little about the roles of… read more here.
Keywords: spatial learning; bc1; learning memory; disease ... See more keywords
Prevention is better than cure: effects of errors on memory performance during spatial learning in healthy aging
Sign Up to like & getrecommendations! Published in 2020 at "Aging Clinical and Experimental Research"
DOI: 10.1007/s40520-020-01603-2
Abstract: Background Healthy aging is accompanied by a decline in learning ability and memory capacity. One widely-studied method to improve learning outcome is by reducing the occurrence of errors during learning (errorless learning; EL). However, there… read more here.
Keywords: healthy aging; spatial learning; tel; memory performance ... See more keywords
Age-related cognitive decline in spatial learning and memory of C57BL/6J mice
Sign Up to like & getrecommendations! Published in 2022 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2021.113649
Abstract: During the last decades, most of the preclinical neurodegenerative research was performed in mouse models of amyloidosis, tauopathies or α-synucleinopathies preferentially maintained on a C57BL/6J background. However, comprehensive neurobehavioural data from C57BL/6J mice outlining the… read more here.
Keywords: c57bl mice; spatial learning; age; c57bl ... See more keywords
Subclinical hypothyroidism in pregnancy rats impaired offspring's spatial learning and memory and the cerebellar development.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2022.02.107
Abstract: Subclinical hypothyroidism (SCH) is a very common preclinical condition during pregnancy. The adverse effect of maternal clinical hypothyroidism (CH) on the nervous system development of offspring is beyond doubt, but it is still controversial in… read more here.
Keywords: spatial learning; group; sch; hypothyroidism ... See more keywords
Effects of dietary polyunsaturated fatty acids on corticosterone concentrations and spatial learning in rats
Sign Up to like & getrecommendations! Published in 2022 at "Behavioural Processes"
DOI: 10.1016/j.beproc.2022.104642
Abstract: Dietary intake of polyunsaturated fatty acids (PUFAs) is crucial for neuronal functions, can positively affect cognition, and reduce glucocorticoid (e.g. corticosterone) concentrations in response to stress. We investigated the effects of walnut oil high in… read more here.
Keywords: corticosterone; polyunsaturated fatty; spatial learning; corticosterone concentrations ... See more keywords
Postconditioning with sevoflurane ameliorates spatial learning and memory deficit via attenuating endoplasmic reticulum stress induced neuron apoptosis in a rat model of hemorrhage shock and resuscitation
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research"
DOI: 10.1016/j.brainres.2018.05.047
Abstract: Hemorrhage shock could initiate endoplasmic reticulum stress (ERS) and then induce neuronal apoptosis. The aim of this study was to investigate whether sevoflurane postconditioning could attenuate brain injury via suppressing apoptosis induced by ERS. Seventy… read more here.
Keywords: spatial learning; apoptosis; hemorrhage shock; learning memory ... See more keywords
Environmental enrichment and amantadine confer individual but nonadditive enhancements in motor and spatial learning after controlled cortical impact injury
Sign Up to like & getrecommendations! Published in 2019 at "Brain Research"
DOI: 10.1016/j.brainres.2019.03.007
Abstract: Environmental enrichment (EE) and amantadine (AMT) enhance motor and cognitive outcome after experimental traumatic brain injury (TBI). However, there are no data on the effects of combining these two therapies. Hence, the aim of the… read more here.
Keywords: spatial learning; amt; cortical impact; enrichment amantadine ... See more keywords
The effect of arsenite on spatial learning: Involvement of autophagy and apoptosis
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2016.12.023
Abstract: ABSTRACT Spatial learning plays a major role in one's information recording. Arsenic is one of ubiquitous environmental toxins with known neurological effects. However, studies investigating the effects of arsenic on spatial learning and related mechanisms… read more here.
Keywords: spatial learning; apoptosis; concentrations sodium; sodium arsenite ... See more keywords