Thermodynamic, Spatial and Methodological Considerations for the Manufacturing of Therapeutic Polymer Nanoparticles
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DOI: 10.1007/s11095-020-2783-4
Abstract: Purpose Evaluate fundamental parameters that dictate the effectiveness of drug loading. Methods A model water-soluble drug lacking ionizable groups, pirfenidone (PFD), was encapsulated through nanoprecipitation in poly(ethylene glycol)-poly(lactic acid) (PEG-PLA)-poly(lactic-co-glycolic acid) (PLGA) NPs. Firstly, the… read more here.
Keywords: methodological considerations; polymer; drug; spatial methodological ... See more keywords