Advances in Spatial Multi‐Omics: A Review of Multi‐Modal Mass Spectrometry Imaging and Laser Capture Microdissection‐LCMS Integration
Sign Up to like & getrecommendations! Published in 2025 at "PROTEOMICS"
DOI: 10.1002/pmic.202400378
Abstract: Mass spectrometry has long been utilized to characterize a variety of biomolecules such as proteins, metabolites, and lipids. Most MS‐based omics studies rely on bulk analysis; however, bulk approaches often overlook low‐abundance molecules that may… read more here.
Keywords: laser; multi omics; spectrometry; mass spectrometry ... See more keywords
Nonlinear modelling and dynamics of spatial multi-link rigid-flexible manipulator with moving platform
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Intelligent Robotics and Applications"
DOI: 10.1007/s41315-024-00344-z
Abstract: The demand for developing lighter manipulators, particularly in various long-reach applications, has surged significantly. In many of these applications, inherent structural flexibilities are unavoidable and lead to vibrations. Consequently, these residual vibrations detrimentally affect working… read more here.
Keywords: rigid flexible; link; manipulator; spatial multi ... See more keywords
A GIS-based spatial multi-index model for flood risk assessment in the Yangtze River Basin, China
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DOI: 10.1016/j.eiar.2020.106397
Abstract: Abstract This paper developed a GIS-based spatial multi-index model for large basin-scale flood risk assessment. In terms of the risk definition proposed by the IPCC, the flood risk in the Yangtze River Basin (YRB) was… read more here.
Keywords: risk; gis based; spatial multi; flood risk ... See more keywords
A general spatial multi-loop linkage optimization model for motion generation with static loading
Sign Up to like & getrecommendations! Published in 2019 at "Inverse Problems in Science and Engineering"
DOI: 10.1080/17415977.2019.1603301
Abstract: ABSTRACT A general spatial multi-loop linkage optimization model for the inverse problem of defect-free motion generation is formulated and demonstrated in this work. The particular linkage of focus is the Revolute-Spherical-Spherical-Revolute-Spherical-Spherical joint (or RSSR-SS) linkage:… read more here.
Keywords: multi loop; optimization model; linkage; spatial multi ... See more keywords
Abstract PL03-04: Forecasting pancreatic carcinogenesis through spatial multi-omics
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DOI: 10.1158/1538-7445.am2023-pl03-04
Abstract: This talk presents a hybrid computational and experimental strategy to uncover interactions between neoplastic cells and the microenvironment during pancreatic carcinogenesis. As pancreatic cancer develops, it forms a complex microenvironment of multiple interacting cells. The… read more here.
Keywords: forecasting pancreatic; spatial multi; pancreatic carcinogenesis; carcinogenesis spatial ... See more keywords
Abstract 5482: Spatial and multi-omic interrogation of the primary and recurrent glioblastoma microenvironment
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-5482
Abstract: Glioblastoma remains as one of the deadliest malignancies with most cases likely to recur. Recent work has focused on characterizing not only glioma cells, but the tumor microenvironment via single-cell and spatial transcriptomic technologies. This… read more here.
Keywords: microenvironment; glioblastoma; spatial multi; recurrent glioblastoma ... See more keywords
Comparative Spatial Distribution Simulation of Plateau Mountain Cultivated Land Based on Spatial Multi-Scale Model, Yunnan Central Urban Agglomeration Area, China
Sign Up to like & getrecommendations! Published in 2023 at "Polish Journal of Environmental Studies"
DOI: 10.15244/pjoes/161379
Abstract: Land use is highly dependent on scale and heterogeneous, serving as an important tool to examine land use change by comparing spatial multi-scale cultivated land models through an appropriate simulation model. In the present study,… read more here.
Keywords: multi scale; spatial multi; scale; land ... See more keywords
Single-Cell and Spatial Multi-Omics Analysis Reveal That Targeting JAG1 in Epithelial Cells Reduces Periodontal Inflammation and Alveolar Bone Loss
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms252413255
Abstract: Mucosal immunity plays a critical role in the pathogenesis of inflammatory immune diseases. This study leverages single-cell RNA sequencing, spatial transcriptomics, and spatial proteomics to compare the cellular mechanisms involved in periodontitis between humans and… read more here.
Keywords: single cell; inflammation; spatial multi; cell spatial ... See more keywords