Function and Spatial Organization of Tumor‐Invasive Human γδ T Cells—What Do We Know?
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Immunology"
DOI: 10.1002/eji.202451075
Abstract: Human gammadelta (γδ) T cells not only infiltrate or reside in healthy tissues but also enter solid cancers. A large body of evidence suggests that γδ T cells can exert potent anti‐tumor effects, although conflicting… read more here.
Keywords: organization tumor; spatial organization; tumor invasive; invasive human ... See more keywords
Spatial organization of astrocyte clones: The role of developmental progenitor timing
Sign Up to like & getrecommendations! Published in 2024 at "Glia"
DOI: 10.1002/glia.24529
Abstract: Astrocytes represent a diverse and morphologically complex group of glial cells critical for shaping and maintaining nervous system homeostasis, as well as responding to injuries. Understanding the origins of astroglial heterogeneity, originated from a limited… read more here.
Keywords: spatial organization; clones role; astroglial clones; astrocyte clones ... See more keywords
Spatial organization of the Schizosaccharomyces pombe genome within the nucleus
Sign Up to like & getrecommendations! Published in 2017 at "Yeast"
DOI: 10.1002/yea.3217
Abstract: The fission yeast Schizosaccharomyces pombe is a useful experimental system for studying the organization of chromosomes within the cell nucleus. S. pombe has a small genome that is organized into three chromosomes. The small size… read more here.
Keywords: spatial organization; microscopy; schizosaccharomyces pombe; pombe genome ... See more keywords
An Algorithm for the Analysis of the 3D Spatial Organization of the Genome.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0664-3_17
Abstract: We present an algorithm, and its MATLAB implementation, based on mathematical methods to detect and localize 3D multicolor DNA FISH spots in fluorescence cell image z-stacks. This algorithm provides a method to measure the relative… read more here.
Keywords: spatial organization; algorithm analysis; organization genome;
MYO6 Regulates Spatial Organization of Signaling Endosomes Driving AKT Activation and Actin Dynamics
Sign Up to like & getrecommendations! Published in 2017 at "Cell Reports"
DOI: 10.1016/j.celrep.2017.05.048
Abstract: Summary APPL1- and RAB5-positive signaling endosomes play a crucial role in the activation of AKT in response to extracellular stimuli. Myosin VI (MYO6) and two of its cargo adaptor proteins, GIPC and TOM1/TOM1L2, localize to… read more here.
Keywords: spatial organization; activation; myo6 regulates; signaling endosomes ... See more keywords
Fraternal Polyandry and Clannish Spatial Organization in a Flightless Island Bird
Sign Up to like & getrecommendations! Published in 2018 at "Current Biology"
DOI: 10.1016/j.cub.2018.03.059
Abstract: Polyandry has been studied in many species, especially birds [1]. Exclusively fraternal polyandry (several full or half-brothers with one unrelated female) is only known in human societies [2, 3], in which it is an important… read more here.
Keywords: spatial organization; polyandry clannish; fraternal polyandry; clannish spatial ... See more keywords
The spatial organization of cGAS-TREX1 interactions.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental cell"
DOI: 10.1016/j.devcel.2021.03.016
Abstract: Coupling DNA sensing to the initiation of immune responses necessitates auxiliary control mechanisms to avoid autoimmunity. A key factor is the exonuclease TREX1, which antagonizes DNA-mediated activation of cGAS. Two studies, by Mohr et al. (2021)… read more here.
Keywords: spatial organization; cgas; trex1; trex1 interactions ... See more keywords
Spatial Organization of Single mRNPs at Different Stages of the Gene Expression Pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.10.010
Abstract: mRNAs form ribonucleoprotein complexes (mRNPs) by association with proteins that are crucial for mRNA metabolism. While the mRNP proteome has been well characterized, little is known about mRNP organization. Using a single-molecule approach, we show that mRNA conformation… read more here.
Keywords: spatial organization; organization single; mrnps different; mrnps ... See more keywords
Mechanical properties of glassy polymers with controlled NP spatial organization
Sign Up to like & getrecommendations! Published in 2020 at "Polymer Testing"
DOI: 10.1016/j.polymertesting.2020.106640
Abstract: Abstract Industrially viable processes enabling effective control of nanoparticle (NP) spatial organization in polymers are vitally important for achieving potential of nano-composites as building blocks of dynamic composites. Here, we report on the small and… read more here.
Keywords: spatial organization; glassy polymers; properties glassy; polymer ... See more keywords
On the spatial organization of hairpin packets in a turbulent boundary layer at low-to-moderate Reynolds number
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Fluid Mechanics"
DOI: 10.1017/jfm.2018.160
Abstract: The present study is devoted to characterizing the coherent organization of vortical structures, which can be fitted into the paradigm of the hairpin-packet model, in the streamwise–wall-normal plane of a canonical turbulent boundary layer at… read more here.
Keywords: spatial organization; boundary layer; turbulent boundary; hairpin packets ... See more keywords
Reconstruction of cell spatial organization from single-cell RNA sequencing data based on ligand-receptor mediated self-assembly
Sign Up to like & getrecommendations! Published in 2020 at "Cell Research"
DOI: 10.1038/s41422-020-0353-2
Abstract: Single-cell RNA sequencing (scRNA-seq) has revolutionized transcriptomic studies by providing unprecedented cellular and molecular throughputs, but spatial information of individual cells is lost during tissue dissociation. While imaging-based technologies such as in situ sequencing show… read more here.
Keywords: spatial organization; single cell; cell rna; rna sequencing ... See more keywords