Spatial regulation of ARL3 and GSF-mediated lipidated cargo trafficking in the primary cilium.
Sign Up to like & getrecommendations! Published in 2025 at "FEBS letters"
DOI: 10.1002/1873-3468.70145
Abstract: Lipid‐modified proteins are essential for ciliary signaling and structure, but their hydrophobic modifications hinder cytosolic transport and selective delivery. GDI‐like solubilizing factors (GSFs), such as PDE6D and UNC119A/B, bind lipid moieties to shield cargo proteins… read more here.
Keywords: arl3; cargo; spatial regulation; primary cilium ... See more keywords
Temporal and spatial regulation of mRNA export: Single particle RNA‐imaging provides new tools and insights
Sign Up to like & getrecommendations! Published in 2017 at "BioEssays"
DOI: 10.1002/bies.201600124
Abstract: The transport of messenger RNAs (mRNAs) from the nucleus to cytoplasm is an essential step in the gene expression program of all eukaryotes. Recent technological advances in the areas of RNA‐labeling, microscopy, and sequencing are… read more here.
Keywords: export; mrna export; regulation mrna; spatial regulation ... See more keywords
Dialectics of nature: Temporal and spatial regulation in material sciences
Sign Up to like & getrecommendations! Published in 2017 at "Nano Research"
DOI: 10.1007/s12274-017-1479-5
Abstract: The cooperative interaction distance measure has been proposed as a novel law pertaining to dialectics of nature, and has been extensively carried out in the design of functional nanomaterials. However, the temporal and spatial dimensions… read more here.
Keywords: temporal regulation; spatial regulation; temporal spatial; nature temporal ... See more keywords
Spatial regulation of signaling by the coordinated action of the protein tyrosine kinases MET and FER.
Sign Up to like & getrecommendations! Published in 2018 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2018.06.006
Abstract: A critical aspect of understanding the regulation of signal transduction is not only to identify the protein-protein interactions that govern assembly of signaling pathways, but also to understand how those pathways are regulated in time… read more here.
Keywords: protein; protein tyrosine; spatial regulation; fer ... See more keywords
Multiple layers of spatial regulation coordinate axonal cargo transport
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2021.03.012
Abstract: Nerve axons are shaped similar to long electric wires to quickly transmit information from one end of the body to the other. To remain healthy and functional, axons depend on a wide range of cellular… read more here.
Keywords: transport; layers spatial; spatial regulation; cargo ... See more keywords
Exploring the impacts of urban growth on carbon storage under integrated spatial regulation: A case study of Wuhan, China
Sign Up to like & getrecommendations! Published in 2020 at "Ecological Indicators"
DOI: 10.1016/j.ecolind.2020.106064
Abstract: Abstract The increasing demand for natural resources due to urban growth has led to sharp conflicts between urban land demand and environmental protection, causing problems such as decrease in the carbon storage of terrestrial ecosystems.… read more here.
Keywords: spatial regulation; growth; urban growth; carbon storage ... See more keywords
Spatial regulation by multiple Gremlin1 enhancers provides digit development with cis-regulatory robustness and evolutionary plasticity
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-25810-1
Abstract: Precise cis-regulatory control of gene expression is essential for normal embryogenesis and tissue development. The BMP antagonist Gremlin1 (Grem1) is a key node in the signalling system that coordinately controls limb bud development. Here, we… read more here.
Keywords: spatial regulation; gremlin1; cis regulatory; development ... See more keywords
Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1101/2022.11.04.515043
Abstract: The glycocalyx component and sialomucin Podocalyxin (PODXL) is required for normal tissue development by promoting apical membranes to form between cells, triggering lumen formation. Elevated PODXL expression is also associated with metastasis and poor clinical… read more here.
Keywords: glycocalyx component; podocalyxin; podxl; spatial regulation ... See more keywords
Plant Protein Disorder: Spatial Regulation, Broad Specificity, Switch of Signaling and Physiological Status
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.904446
Abstract: its nucleus interaction partners may be a key feature for IDPs/IDRs in downstream signaling. read more here.
Keywords: spatial regulation; protein disorder; disorder spatial; plant protein ... See more keywords