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Spatiotemporal Regulation of RhoA during Cytokinesis

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0 Published in 2018 at "Current Biology"

DOI: 10.1016/j.cub.2018.03.045

Abstract: The active form of the small GTPase RhoA is necessary and sufficient for formation of a cytokinetic furrow in animal cells. Despite the conceptual simplicity of the process, the molecular mechanisms that control it are… read more here.

Keywords: spatiotemporal regulation; rhoa; cytokinesis; regulation rhoa ... See more keywords

Spatiotemporal regulation of hydrogen sulfide signaling in the kidney

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0 Published in 2021 at "Redox Biology"

DOI: 10.1016/j.redox.2021.101961

Abstract: Hydrogen sulfide (H2S) has long been recognized as a putrid, toxic gas. However, as a result of intensive biochemical research in the past two decades, H2S is now considered to be the third gasotransmitter alongside… read more here.

Keywords: hydrogen sulfide; spatiotemporal regulation; h2s; regulation ... See more keywords

Spatiotemporal Regulation of Metal Ions in the Polymerase Chain Reaction

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1 Published in 2022 at "ACS Omega"

DOI: 10.1021/acsomega.2c04507

Abstract: The polymerase chain reaction (PCR) has been widely used in medical diagnosis and forensic identification due to its ultrahigh sensitivity and signal amplification. Metal ions (i.e., Cu2+, Zn2+) have been considered PCR inhibitors and rarely… read more here.

Keywords: metal ions; chain reaction; polymerase chain; spatiotemporal regulation ... See more keywords

Spatiotemporal regulation of peripheral T cell tolerance

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2 Published in 2023 at "Science"

DOI: 10.1126/science.adg6425

Abstract: The incomplete removal of T cells that are reactive against self-proteins during their differentiation in the thymus requires mechanisms of tolerance that prevent their effector function within the periphery. A further challenge is imposed by… read more here.

Keywords: cell; peripheral cell; regulation peripheral; tolerance ... See more keywords

Spatiotemporal Regulation of FMNL2 by N-Terminal Myristoylation and C-Terminal Phosphorylation Drives Rapid Filopodia Formation

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1 Published in 2023 at "Biomolecules"

DOI: 10.3390/biom13030548

Abstract: The actin nucleating and polymerizing formin-like 2 (FMNL2) is upregulated in several cancers and has been shown to play important roles in cell migration, invasion, cell–cell adhesion and filopodia formation. Here, using structured illumination microscopy… read more here.

Keywords: filopodia formation; terminal myristoylation; spatiotemporal regulation; formation ... See more keywords