Suppression of osteoclast multinucleation via a posttranscriptional regulation–based spatiotemporally selective delivery system
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DOI: 10.1126/sciadv.abn3333
Abstract: Redundancy of multinucleated mature osteoclasts, which results from the excessive fusion of mononucleated preosteoclasts (pOCs), leads to osteolytic diseases such as osteoporosis. Unfortunately, the currently available clinical drugs completely inhibit osteoclasts, thus interfering with normal… read more here.
Keywords: poc; selective delivery; delivery system; spatiotemporally selective ... See more keywords