A cross-species spatiotemporal proteomic analysis identifies UBE3A-dependent signaling pathways and targets
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DOI: 10.1038/s41380-022-01484-z
Abstract: Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by the loss of neuronal E3 ligase UBE3A. Restoring UBE3A levels is a potential disease-modifying therapy for AS and has recently entered clinical trials. There is… read more here.
Keywords: analysis; spatiotemporal proteomic; species spatiotemporal; analysis identifies ... See more keywords