Cysteine-Specific 18F and NIR Dual Labeling of Peptides via Vinyltetrazine Bioorthogonal Conjugation for Molecular Imaging.
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DOI: 10.1021/acs.jmedchem.4c02165
Abstract: Radiolabeled peptides are vital for positron emission tomography (PET) imaging, yet the 18F-labeling peptides remain challenging due to harsh conditions and time-consuming premodification requirements. Herein, we developed a novel vinyltetrazine-mediated bioorthogonal approach for highly efficient… read more here.
Keywords: cysteine specific; nir dual; specific 18f; labeling peptides ... See more keywords