Potent and Specific Activators for Mitochondrial Sirtuins Sirt3 and Sirt5.
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DOI: 10.1021/acs.jmedchem.2c01215
Abstract: Sirtuins are NAD+-dependent protein deacylases involved in metabolic regulation and aging-related diseases. Specific activators for seven human Sirtuin isoforms would be important chemical tools and potential therapeutic drugs. Activators have been described for Sirt1 and… read more here.
Keywords: sirt3 sirt5; mitochondrial sirtuins; activators mitochondrial; specific activators ... See more keywords