Acidity-triggered charge-convertible nanoparticles that can cause bacterium-specific aggregation in situ to enhance photothermal ablation of focal infection.
Sign Up to like & getrecommendations! Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2016.11.045
Abstract: Focal infections that are caused by antibiotic-resistant bacteria are becoming an ever-growing challenge to human health. To address this challenge, a pH-responsive amphiphilic polymer of polyaniline-conjugated glycol chitosan (PANI-GCS) that can self-assemble into nanoparticles (NPs)… read more here.
Keywords: pani gcs; gcs; bacterium specific; gcs nps ... See more keywords
Bacterial-Specific Aggregation and Killing of Immunomodulatory Host Defense Peptides
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DOI: 10.3390/ph14090839
Abstract: This study involves the design and development of disulfide bridge-linked antimicrobial peptides using the host defense protein Angiogenin 4 (chAng4) as a template. The mini peptides derived from chAng4 (mCA4s) were evaluated for their antibacterial… read more here.
Keywords: bacterial specific; host defense; aggregation killing; specific aggregation ... See more keywords