Lineage-Specific Alterations in Gynecologic Neoplasms with Choriocarcinomatous Differentiation: Implications for Origin and Therapeutics
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DOI: 10.1158/1078-0432.ccr-18-4278
Abstract: Purpose: Choriocarcinoma is most commonly gestational (androgenetic or biparental) but can be of germ cell origin or can develop as a component of a somatic neoplasm (genetically related to the patient). The latter type are… read more here.
Keywords: expression; neoplasms choriocarcinomatous; differentiation; specific alterations ... See more keywords
Kinase Inhibitor Treatment of Patients with Advanced Cancer Results in High Tumor Drug Concentrations and in Specific Alterations of the Tumor Phosphoproteome
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DOI: 10.3390/cancers12020330
Abstract: Identification of predictive biomarkers for targeted therapies requires information on drug exposure at the target site as well as its effect on the signaling context of a tumor. To obtain more insight in the clinical… read more here.
Keywords: specific alterations; drug; tumor drug; patients advanced ... See more keywords