Specific amino acids from the broad C-terminal region of BMP-2 are crucial for osteogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Bone Reports"
DOI: 10.1016/j.bonr.2021.101092
Abstract: The shortest functional domains of growth factor Bone Morphogenetic Protein 2 (BMP-2) that are dynamical implicated in osteogenesis have been investigated and well characterized. In particular, the broad C-terminal region expanding from Val63 to Arg114… read more here.
Keywords: amino acids; terminal region; broad terminal; osteogenesis ... See more keywords
Automated Specific Amino Acid Footprinting Mass Spectrometry: Repurposing an HDX Platform for Determining Reagent Feasibility.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c02073
Abstract: Protein footprinting is a mass spectrometry (MS)-based approach to measure protein conformational changes. One approach, specific amino acid labeling, imparts often an irreversible modification to protein side chains but requires careful selection of the reactive… read more here.
Keywords: mass spectrometry; footprinting mass; amino acid; specific amino ... See more keywords
Indigenous Proline is a Two-Dimensional Safety-Relief Valve in Balancing Specific Amino Acids in Rice under Hexavalent Chromium Stress.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c02575
Abstract: This study highlights the roles of different N sources (N starvation [-N], nitrate [+NO3-], and ammonium [+NH4+]) in specific amino acids involved in rice proline (Pro) metabolism under hexavalent chromium [Cr(VI)] stress. In treatment with… read more here.
Keywords: amino acids; rice; chromium stress; hexavalent chromium ... See more keywords
Chemoselective and enantioselective fluorescent identification of specific amino acid enantiomers.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc02363f
Abstract: The enantiomers of chiral amino acids play versatile roles in biological systems including humans. They are also very useful in the asymmetric synthesis of diverse chiral organic compounds. Therefore, identifying a specific amino acid and… read more here.
Keywords: amino acids; acid; amino acid; fluorescence ... See more keywords
Site-specific amino acid substitution in dodecameric peptides determines the stability and unfolding of c-MYC quadruplex promoting apoptosis in cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky824
Abstract: Abstract c-MYC proto-oncogene harbours a transcription-inhibitory quadruplex-forming scaffold (Pu27) upstream P1 promoter providing anti-neoplastic therapeutic target. Previous reports showed the binding profile of human Cathelicidin peptide (LL37) and telomeric G-quadruplex. Here, we truncated the quadruplex-binding… read more here.
Keywords: amino acid; myc quadruplex; site specific; acid substitution ... See more keywords
Immunogenic Modification of Ligilactobacillus agilis by Specific Amino Acid Substitution of Flagellin
Sign Up to like & getrecommendations! Published in 2022 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.01277-22
Abstract: The interactions between gut microbes and immune cells play an important role in the health and disease of hosts. Ligilactobacillus agilis is a flagellated commensal bacterium found in the gut of mammals and birds. However,… read more here.
Keywords: tlr5 recognition; amino acid; ligilactobacillus agilis; specific amino ... See more keywords
Cadmium toxicity induced contrasting patterns of concentrations of free sarcosine, specific amino acids and selected microelements in two Noccaea species
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0177963
Abstract: Cadmium (Cd) toxicity affects numerous metabolic processes in plants. In the presence of Cd, plants accumulate specific amino acids which may be beneficial to developing Cd tolerance. Our study aimed to characterize the changes in… read more here.
Keywords: amino; amino acids; selected microelements; cadmium toxicity ... See more keywords
Ketone Body Exposure of Cardiomyocytes Impairs Insulin Sensitivity and Contractile Function through Vacuolar-Type H+-ATPase Disassembly—Rescue by Specific Amino Acid Supplementation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232112909
Abstract: The heart is metabolically flexible. Under physiological conditions, it mainly uses lipids and glucose as energy substrates. In uncontrolled diabetes, the heart switches towards predominant lipid utilization, which over time is detrimental to cardiac function.… read more here.
Keywords: atpase disassembly; function; ketone; specific amino ... See more keywords
Sensing Properties of NH2-MIL-101 Series for Specific Amino Acids via Turn-On Fluorescence
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26175336
Abstract: Metal–organic frameworks (MOFs) have been demonstrated to be desired candidates for sensing definite species owing to their tunable composition, framework structure and functionality. In this work, the NH2-MIL-101 series was utilized for sensing specific amino… read more here.
Keywords: nh2 mil; amino acids; fluorescence; specific amino ... See more keywords