Straightforward protocol for allele-specific chromatin conformation capture.
Sign Up to like & getrecommendations! Published in 2020 at "Gene"
DOI: 10.1016/j.gene.2020.145185
Abstract: A key advance in our understanding of gene regulation came with the finding that the genome undergoes three-dimensional nuclear folding in a genetically determined process. This 3D conformation directly influences the association between enhancers and… read more here.
Keywords: chromatin; specific chromatin; conformation; allele specific ... See more keywords
Allele specific chromatin signals, 3D interactions, and refined motif predictions for immune and B cell related diseases
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Human Genetics"
DOI: 10.1038/s41431-019-0404-7
Abstract: Allele specific chromatin signals, 3D interactions, and refined motif predictions for immune and B cell related diseases read more here.
Keywords: specific chromatin; interactions refined; signals interactions; allele specific ... See more keywords
Locus-specific chromatin isolation
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Molecular Cell Biology"
DOI: 10.1038/s41580-020-0217-0
Abstract: Identifying factors bound to specific genomic loci in an unbiased manner is the holy grail of chromatin research, because it would provide an ultimate description of locus function. In this Comment, we explain why purifying… read more here.
Keywords: chromatin isolation; chromatin; locus specific; specific chromatin ... See more keywords