WT1-specific cytotoxic T lymphocytes induced by activated B cells as apc
Sign Up to like & getrecommendations! Published in 2019 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2019.03.352
Abstract: Background & Aim WT1 is highly expressed in many malignancies including leukemia and targeting WT1 as a Tumor Associated Antigen (TAA) in cancer immunotherapy is attractive. In this study, we induced WT1-specific cytotoxic T lymphocytes… read more here.
Keywords: activated cells; specific ctls; antigen; wt1 specific ... See more keywords
High TCR Degeneracy Enhances Antiviral Efficacy of HTLV-1-Specific CTLs by Targeting Variant Viruses in HAM Patients
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DOI: 10.3390/ijms26146602
Abstract: T-cell receptors (TCRs) exhibit degeneracy, enabling individual TCRs to recognize multiple altered peptide ligands (APLs) derived from a single cognate antigen. This characteristic has been involved in the pathogenesis of autoimmune diseases through cross-reactivity between… read more here.
Keywords: htlv; degeneracy; tcr degeneracy; specific ctls ... See more keywords