A systematic evaluation of cell-type-specific differential methylation analysis in bulk tissue
Sign Up to like & getrecommendations! Published in 2025 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbaf170
Abstract: Abstract We conducted a systematic assessment of computational models—CellDMC, TCA, HIRE, TOAST, and CeDAR—for detecting cell-type-specific differential methylation CpGs in bulk methylation data profiled using the Illumina DNA Methylation BeadArrays. This assessment was performed through… read more here.
Keywords: type specific; methylation; differential methylation; usepackage ... See more keywords
Predicting Distant Cancer Metastasis Using a Weighted Gene Interaction Network and Sample-Specific Differential Correlations
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Bioinformatics and Computational Biology"
DOI: 10.1142/s0219720025500246
Abstract: Predicting metastasis in early stages of cancer plays a crucial role in effectively controlling cancer progression and thereby improving patient survival outcomes. Although several computational methods have been developed to predict cancer metastasis, most focus… read more here.
Keywords: cancer; sample specific; specific differential; model ... See more keywords