Cell type-specific epigenetic links to schizophrenia risk in the brain
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DOI: 10.1186/s13059-019-1747-7
Abstract: BackgroundThe importance of cell type-specific epigenetic variation of non-coding regions in neuropsychiatric disorders is increasingly appreciated, yet data from disease brains are conspicuously lacking. We generate cell type-specific whole-genome methylomes (N = 95) and transcriptomes (N = 89) from… read more here.
Keywords: type specific; specific epigenetic; brain; cell ... See more keywords
FeatSNP: An Interactive Database for Brain-Specific Epigenetic Annotation of Human SNPs
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2019.00262
Abstract: FeatSNP is an online tool and a curated database for exploring 81 million common SNPs’ potential functional impact on the human brain. FeatSNP uses the brain transcriptomes of the human population to improve functional annotation… read more here.
Keywords: annotation human; specific epigenetic; brain specific; database ... See more keywords