Bdyof is a Y-chromosome-specific gene required for male development in Bactrocera dorsalis.
Sign Up to like & getrecommendations! Published in 2024 at "Pest management science"
DOI: 10.1002/ps.8577
Abstract: BACKGROUND In many organisms, the Y chromosome contains important genes associated with sex determination and male reproductive development. However, there have been few studies of Y-chromosome-specific genes in non-model species due to the incomplete information… read more here.
Keywords: specific gene; chromosome specific; development; bactrocera dorsalis ... See more keywords
C/EBPß Isoform Specific Gene Regulation: It’s a Lot more Complicated than you Think!
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Mammary Gland Biology and Neoplasia"
DOI: 10.1007/s10911-020-09444-5
Abstract: It has been almost 30 years since C/EBPß was discovered. Seminal studies have shown that C/EBPß is a master regulator of mammary gland development and has been shown to control and influence proliferation and differentiation through… read more here.
Keywords: ebp isoform; isoform; isoform specific; breast cancer ... See more keywords
A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular cell"
DOI: 10.1016/j.molcel.2021.01.041
Abstract: Organismal development and cell differentiation critically depend on chromatin state transitions. However, certain developmentally regulated genes lack histone 3 lysine 9 and 27 acetylation (H3K9ac and H3K27ac, respectively) and histone 3 lysine 4 (H3K4) methylation,… read more here.
Keywords: tissue specific; histone lysine; lysine; specific gene ... See more keywords
Pathogen Recognition-Driven Dendritic Cell-Specific Gene Silencing and Editing.
Sign Up to like & getrecommendations! Published in 2023 at "Nano letters"
DOI: 10.1021/acs.nanolett.3c00015
Abstract: Dendritic cells (DCs) play an essential role in both the induction of the immune response and the maintenance of immune tolerance, with any malfunction of DCs potentially causing several diseases. While gene-based therapy for DC… read more here.
Keywords: recognition; gene silencing; specific gene; gene ... See more keywords
Organ-Specific Gene Expression Control Using DNA Origami-Based Nanodevices
Sign Up to like & getrecommendations! Published in 2024 at "Nano Letters"
DOI: 10.1021/acs.nanolett.4c02104
Abstract: Nanodevices that function in specific organs or cells are one of the ultimate goals of synthetic biology. The recent progress in DNA nanotechnology such as DNA origami has allowed us to construct nanodevices to deliver… read more here.
Keywords: specific gene; organ specific; dna; dna origami ... See more keywords
Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-04295-5
Abstract: The development of malaria parasites throughout their various life cycle stages is coordinated by changes in gene expression. We previously showed that the three-dimensional organization of the Plasmodium falciparum genome is strongly associated with gene… read more here.
Keywords: gene families; gene expression; specific gene; malaria parasites ... See more keywords
Allele-specific gene expression in F1 hybrid mice reveals structural variants affecting macrophage characteristics
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-21643-w
Abstract: Genetic diversity underlies the foundation for variations in gene expression, resulting in diverse phenotypic traits. In this study, we investigated the effect of genetic variation on macrophage function using two genetically distinct mouse strains, C57BL/6… read more here.
Keywords: specific gene; gene expression; macrophage; allele specific ... See more keywords
Spatial transcriptomic profiling of the human fallopian tube epithelium reveals region-specific gene expression patterns
Sign Up to like & getrecommendations! Published in 2025 at "Communications Biology"
DOI: 10.1038/s42003-025-07871-w
Abstract: The fallopian tube (FT) plays a crucial role in fertility, gynecological health, and high-grade serous ovarian cancer (HGSOC) development. Despite its importance, the spatial transcriptome of the FT’s distinct anatomical regions (fimbria, infundibulum, ampulla, and… read more here.
Keywords: region specific; specific gene; expression; fallopian tube ... See more keywords
Adaptive NetworkProfiler for Identifying Cancer Characteristic-Specific Gene Regulatory Networks.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Computational Biology"
DOI: 10.1089/cmb.2017.0120
Abstract: Abstract There is currently much discussion about sample (patient)-specific gene regulatory network identification, since the efficiently constructed sample-specific gene networks lead to effective personalized cancer therapy. Although statistical approaches have been proposed for inferring gene… read more here.
Keywords: networkprofiler; gene regulatory; specific gene; cancer ... See more keywords
Inferring cell-type-specific gene regulatory network from cellular transcriptomics data with GeneLink+
Sign Up to like & getrecommendations! Published in 2025 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbaf359
Abstract: Abstract Deciphering cell-type-specific gene regulatory networks (ctGRNs) is crucial for elucidating fundamental biological processes, such as tissue development and cancer progression. However, accurately inferring ctGRNs from high-dimensional transcriptomic data poses a significant challenge, primarily due… read more here.
Keywords: type specific; gene; cell type; specific gene ... See more keywords
Gene behaviors-based network enrichment analysis and its application to reveal immune disease pathways enriched with COVID-19 severity-specific gene networks
Sign Up to like & getrecommendations! Published in 2025 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btaf378
Abstract: Abstract Motivation Gene network analysis is essential for understanding the complex mechanisms underlying diseases, which often involve disruptions in molecular networks rather than individual genes. Despite the availability of large-scale omics datasets and computational tools… read more here.
Keywords: specific gene; analysis; network; gene ... See more keywords