Sex-specific genetic diversity is shaped by cultural factors in Inner Asian human populations.
Sign Up to like & getrecommendations! Published in 2017 at "American journal of physical anthropology"
DOI: 10.1002/ajpa.23151
Abstract: OBJECTIVES Sex-specific genetic structures have been previously documented worldwide in humans, even though causal factors have not always clearly been identified. In this study, we investigated the impact of ethnicity, geography and social organization on… read more here.
Keywords: geography; genetic diversity; specific genetic; sex specific ... See more keywords
Distinguishing pedigree relationships via multi-way identity by descent sharing and sex-specific genetic maps.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2020.12.004
Abstract: The proportion of samples with one or more close relatives in a genetic dataset increases rapidly with sample size, necessitating relatedness modeling and enabling pedigree-based analyses. Despite this, relatives are generally unreported and current inference… read more here.
Keywords: specific genetic; identity descent; sex specific; genetic maps ... See more keywords
Sex-specific genetic effects across biomarkers
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Human Genetics"
DOI: 10.1038/s41431-020-00712-w
Abstract: Sex differences have been shown in laboratory biomarkers; however, the extent to which this is due to genetics is unknown. In this study, we infer sex-specific genetic parameters (heritability and genetic correlation) across 33 quantitative… read more here.
Keywords: specific genetic; genetic effects; genetics; sex specific ... See more keywords
Patient‐specific genetic factors predict treatment failure in sofosbuvir‐treated patients with chronic hepatitis C
Sign Up to like & getrecommendations! Published in 2022 at "Liver International"
DOI: 10.1111/liv.15175
Abstract: According to pivotal clinical trials, cure rates for sofosbuvir‐based antiviral therapy exceed 96%. Treatment failure is usually assumed to be because of virological resistance‐associated substitutions or clinical risk factors, yet the role of patient‐specific genetic… read more here.
Keywords: specific genetic; treatment failure; treatment; genetic factors ... See more keywords
Identification of female-specific genetic variants for metabolic syndrome and its component traits to improve the prediction of metabolic syndrome in females
Sign Up to like & getrecommendations! Published in 2019 at "BMC Medical Genetics"
DOI: 10.1186/s12881-019-0830-y
Abstract: BackgroundMetabolic syndrome (MetS), defined as a cluster of metabolic risk factors including dyslipidemia, insulin-resistance, and elevated blood pressure, has been known as partly heritable. MetS effects the lives of many people worldwide, yet females have… read more here.
Keywords: specific genetic; mets females; genetic variants; metabolic syndrome ... See more keywords
Identification of Sex-Specific Genetic Polymorphisms Associated with Asthma in Middle-Aged and Older Canadian Adults: An Analysis of CLSA Data
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Asthma and Allergy"
DOI: 10.2147/jaa.s404670
Abstract: Purpose Asthma is a chronic heterogeneous respiratory disease resulting from a complex interplay between genetic variations and environmental exposures. There are sex disparities in the prevalence and severity of asthma in males and females. Asthma… read more here.
Keywords: asthma; associated asthma; specific genetic; sex ... See more keywords
Phylogenomics and Comparative Genomics Highlight Specific Genetic Features in Ganoderma Species
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8030311
Abstract: The Ganoderma species in Polyporales are ecologically and economically relevant wood decayers used in traditional medicine, but their genomic traits are still poorly documented. In the present study, we carried out a phylogenomic and comparative… read more here.
Keywords: phylogenomics comparative; comparative genomics; genomics highlight; highlight specific ... See more keywords