Species-specific genomic sequences for classification of bacteria
Sign Up to like & getrecommendations! Published in 2020 at "Computers in biology and medicine"
DOI: 10.1016/j.compbiomed.2020.103874
Abstract: Modern bacterial classification relies on genomic relatedness. Genetic variation in bacterial populations present a big challenge for taxonomic classification and recently several bacterial species have been reclassified based on the intra-species genome comparison. These were… read more here.
Keywords: bacterial species; classification; specific genomic; genome comparison ... See more keywords
Primary Plasma Cell Leukemia displaying t(11;14) have specific genomic, transcriptional and clinical feature.
Sign Up to like & getrecommendations! Published in 2022 at "Blood"
DOI: 10.1182/blood.2021014968
Abstract: Primary plasma cell leukemia (pPCL) is an aggressive form of multiple myeloma (MM) that has not benefited from recent therapeutic advances in the field. Because very rare and heterogeneous, it remains poorly understood at the… read more here.
Keywords: specific genomic; plasma cell; cell leukemia; plasma ... See more keywords
Emerging Targeted Therapy for Specific Genomic Abnormalities in Acute Myeloid Leukemia
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23042362
Abstract: We describe recent updates of existing molecular-targeting agents and emerging novel gene-specific strategies. FLT3 and IDH inhibitors are being tested in combination with conventional chemotherapy for both medically fit patients and patients who are ineligible… read more here.
Keywords: emerging targeted; therapy; genomic abnormalities; targeted therapy ... See more keywords