Quantitative Site-Specific Glycoproteomics Reveals Glyco-Signatures for Breast Cancer Diagnosis.
Sign Up to like & getrecommendations! Published in 2024 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.4c03069
Abstract: Intact glycopeptide characterization by mass spectrometry has proven to be a versatile tool for site-specific glycoproteomics analysis and biomarker screening. Here, we present a method using a new model of a Q-TOF instrument equipped with… read more here.
Keywords: breast cancer; specific glycoproteomics; glyco signatures; site ... See more keywords
Structure-Specific N-Glycoproteomics Characterization of NIST Monoclonal Antibody Reference Material 8671.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00027
Abstract: The characteristics of monoclonal antibodies (mAbs) cohering various function effectors show great expectation in therapy. Glycosylation, one of the common post-translational modifications, deeply influences cohesion. It is necessary to grasp monosaccharide composition/sequence and glycan structures… read more here.
Keywords: structure; structure specific; characterization nist; specific glycoproteomics ... See more keywords
High-throughput site-specific N-glycoproteomics reveals glyco-signatures for liver disease diagnosis
Sign Up to like & getrecommendations! Published in 2022 at "National Science Review"
DOI: 10.1093/nsr/nwac059
Abstract: ABSTRACT The glycoproteome has emerged as a prominent target for screening biomarkers, as altered glycosylation is a hallmark of cancer cells. In this work, we incorporated tandem mass tag labeling into quantitative glycoproteomics by developing… read more here.
Keywords: throughput site; specific glycoproteomics; high throughput; liver diseases ... See more keywords