Articles with "specific glycosylation" as a keyword



Purification and site-specific N-glycosylation analysis of human recombinant butyrylcholinesterase from Nicotiana benthamiana

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Published in 2019 at "Biochemical Engineering Journal"

DOI: 10.1016/j.bej.2018.11.004

Abstract: Abstract Butyrylcholinesterase (BChE) is a glycosylated serine hydrolase found in human serum that has been shown to protect against various cholinesterase-inhibiting organophosphate nerve agents. The supply of plasma-derived butyrylcholinesterase (hBChE) is constrained by the availability… read more here.

Keywords: purification; specific glycosylation; nicotiana benthamiana; butyrylcholinesterase ... See more keywords

Site-Specific Glycosylation Analysis of Human and Murine Fcγ Receptor II Family Members Reveals Variant-Specific N-Glycosylation

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Published in 2024 at "Journal of Proteome Research"

DOI: 10.1021/acs.jproteome.4c00141

Abstract: Fcγ-receptors (FcγRs) including FcγRII (CD32) gene family members are expressed on leukocytes, bind the crystallizable fragment (Fc) region of immunoglobulin G (IgG), and bridge humoral and cellular immunity. FcγRIIA and FcγRIIB have opposing roles, with… read more here.

Keywords: family; riia; specific glycosylation; site specific ... See more keywords

Uncovering missing glycans and unexpected fragments with pGlycoNovo for site-specific glycosylation analysis across species

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Published in 2024 at "Nature Communications"

DOI: 10.1038/s41467-024-52099-7

Abstract: Precision mapping of site-specific glycans using mass spectrometry is vital in glycoproteomics. However, the diversity of glycan compositions across species often exceeds database capacity, hindering the identification of rare glycans. Here, we introduce pGlycoNovo, a… read more here.

Keywords: uncovering missing; site; specific glycosylation; site specific ... See more keywords